VAC_88_2024 - PHD Student - Endothelial Pathobiology and Microenvironment Group

Temporary, Full-time · IJC Can Ruti

Your mission

The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.  

 The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII).

 The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services.  The IJC has six locations integrated into reference hospitals: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.

The Chromatin Biology Laboratory led by PHD Student, This contract is part of the grant PID2023-152319OB-I00 funded by MCIU/ AEI / 10.13039/501100011033 / FSE+”.

MAIN RESPONSIBILITIES

  • Study the role of PIK3CA mutations in the vasculature.

  • Generate and maintain a mouse colony of PIK3CA-related vascular malformation models. 

  • Perform preclinical studies in PIK3CA-realted vascular malformations experimental settings.

  • Characterize the functional impact of PIK3CA mutations in cultured endothelial cells.

  • Perform scRNAseq experiments and analysis.


Your profile

WHAT WE NEED

  • MSc in Biology, Biomedicine or similar.

  • A high level of motivation and interest.

  • Excellent communication and organizational skills.

  • Good level of oral and written English.

  • Experience in cellular and molecular biology, stress response. 

  • Good academic records that allow the candidate to apply for competitive PhD calls.

  • Previous experience in stress response and/or sirtuin biology, as well as proteomic and/or genomic analysis, would be highly valued.

Why us?

WHAT WE OFFER

  • A FPI PhD position for 4 years funded by MCIN/AEI/10.13039/501100011033 and  FSE+.

  • The stimulating environment of the Barcelona metropolitan area.

  • An exciting and innovative research project.

  • Incorporation in a well-established, dynamic and highly motivated team.  

  • Working in the outstanding multidisciplinary research environment of the Josep Carreras Leukaemia Research Institute.

How to apply?

DEADLINE FOR APPLICATIONS 

Please submit your application by December 15th, 2024. 

Deadline

EVALUATION CRITERIA

The evaluation criteria for the selection process are as follows:

  • Criterion 1. Academic and/or scientific-technical background of the candidate (up to 50 points). 

    • Sub-criterion 1.a): Scientific-technical contributions (up to 45 points). The
    • Sub-criterion 1.b): Mobility and internationalization (up to 5 points). The relevance and impact of the candidate's stays at national and international centers and/or in the industrial sector on their research career will be assessed, considering the prestige of the host institution and the activities undertaken there.
  •  Criterion 2. Suitability of the candidate to the research activities to be carried out (up to 50 points). The candidate's suitability for the program, project, or research activities to be developed will be evaluated based on their prior education and experience. The added value that carrying out the project will represent for the candidate's research career, as well as the value contributed to the center and the receiving team, will be taken into account.

About us
What makes us different? 

The mission of the Josep Carreras Institute is to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of cancer, with a special emphasis on leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases.

The IJC’s vision is to be a world-class reference and excellent research multicampus that contributes to the improvement of results, and the cure of patients affected by leukemia and other malignant hemopathies, through innovation, sustainability, social responsibility, talent, and professional experience.


HR Excellence

In 2019, IJC was honored with the “Human Resources Excellence in Research Award” by the European Commission, recognizing the alignment of our human resources policies with the European Charter for Researchers and Code of Conduct for the Recruitment of Researchers. The Human Resources Strategy for Researchers (HRS4R) guides research centers of excellence in implementing and upholding these standards within their policies, emphasizing training, professional development, and mobility opportunities.

The IJC’s commitment to these values and principles strengthens our internal policies and ensures that our members have the optimal conditions and environment for their professional development.

The IJC is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, or other legally protected characteristics.

We are looking forward to hearing from you!
Thank you for your interest in IJC. Please fill out the following short form. 
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