Your mission
The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.
The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII).
The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services. The IJC has six locations integrated into reference hospitals: Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.
Research Description
We are seeking a student with a master’s in Bioinformatics to join the Transcriptional Dynamics in Leukemia group, led by Dr. Sergi Cuartero. The team investigates how transcriptional regulators and chromatin modifiers contribute to normal blood differentiation and how their mutations lead to leukemia. Our team includes both experimental and computational researchers, and the candidate will be guided by a senior bioinformatician in the group. The main tasks will involve analysing sequencing data generated in the lab with the goal of uncovering novel mechanisms of transcriptional regulation in leukemia. This contract is part of the grant PID2023-151180OB-I00 funded by MCIU/ AEI / 10.13039/501100011033 / FSE+”
MAIN RESPONSIBILITIES
- Conducting a project aimed at understanding the mechanisms underlying gene expression deregulation in normal blood cells and leukemia.
- Experimental design and deep exploration of complex datasets.
- Analysis of next-generation sequencing datasets (RNA-seq, ATAC-seq, Hi-C).
- Integration of epigenomic data with large-scale, public transcriptomic datasets.
- Management of the databases related to the project.