VAC_36_2024_PREDOCTORAL RESEARCHER_ Mechanisms of Cancer and Ageing Lab (South)

Temporary, Full-time · IJC Can Ruti

Your mission
The Josep Carreras Leukaemia Research Institute (IJC) is a non-profit research institute based in Barcelona dedicated to advancing the understanding of leukemia and related disorders, in collaboration with the University of Barcelona and the Autonomous University of Barcelona. The IJC has laboratories in 5 clinical campuses: i) Hospital Clínic, ii) Hospital de Sant Pau and iii) Hospital Germans Trias Pujol iv) Hospital del Mar and v) Hospital Josep Trueta Girona. IJC serves as a collaborative center for basic researchers and physicians to work together on fundamental clinical and biological aspects of leukemia. The IJC offers an excellent work environment based on a multidisciplinary fusion of state-of-the-art ideas and facilities.
For further information, please, visit our webpage: http://www.carrerasresearch.org/en and the Josep Carreras nonprofit organization: https://www.fcarreras.org/en.
The Josep Carreras Leukemia Research Institute Can Ruti is looking for a PhD student for the Mechanisms of Cancer and Ageing Lab (South) group led by Dr. Salvador Macip. 

In the MoCaA Lab (http://lab.macip.org) we study the mechanisms that determine resistance to treatment and relapse in B cell malignancies and the molecular pathways involved in age-related diseases, with particular emphasis on the role of senescent cells in cancer and ageing phenotypes. We also investigate prognostic/diagnostic markers of ageing and anti-senescent therapies for healthy ageing and as adjuvant treatments for leukemia. 
 
This project is an international collaboration with the Vogler lab (https://vogler-lab.de/) at the Frankfurt Foundation for Children with Cancer. Our goal is to determine the role of senescence as a potential mechanism for resistance and relapse in Diffuse large B cell lymphoma (DLBCL), the most common form of lymphoma. Despite initial response to current treatments, many DLBCL patients relapse, for reasons not known. Our preliminary data suggests senescent cell accumulation may play a part. We will use a multidisciplinary approach, including genomics, proteomics and work on patient samples, to study this link and propose improved therapeutic strategies for DLBCL.

This contract is linked to the project "Targeting senescence as anti-lymphoma strategy" funded by Deutsche José Carreras Leukämie Stiftung.
Your profile
We are seeking a highly motivated and talented Predoctoral Researcher to join our research team and contribute to this exciting project. Previous work on leukemia or lymphoma and/or experience with cell culture is desirable.
 
General skills
  • A committed scientist with a competitive scientific record and experience in biology, biomedicine or related disciplines. 
  • A high level of motivation and interest in biomedical research.
  • Good communication skills.
  • Fluent in English
Technical skills
  • Degree in Biology or Biochemistry (or related field).
  • MSc in Cell Biology, hematology or related field.
Responsibilities
  • To design and perform experiments to advance the project.
  • To process the data obtained and prepare figures.
  • To present and discuss the results in lab meetings and conferences.
  • To complete and defend a thesis at the end of the project.
Why us?
  • Full-time contract
  • 3-year predoctoral contract
  • Be part of a young, collaborative, and international work environment with cutting-edge technologies and interdisciplinary teams of scientists, including experts in medicine, immunology, genomics, and bioinformatics.
  • An exciting and innovative research project.
  • The stimulating environment of the Barcelona metropolitan area.
  • 23 holidays and 11 personal days.
Deadline
Please submit your application by 24th June, 2024
About us
What makes us different?
Our mission is to investigate the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies through innovation to cure them.
The vision of the Josep Carre
ras Leukaemia Research Institute is to be a world-class reference and excellent research multicampus that contributes to the improvement of results, and the cure of patients affected by leukemia and other malignant hemopathies, through innovation, sustainability, social responsibility, talent, and professional experience.

HR Excellence
The  European  Commission awarded the IJC the  HR Excellence seal in July 2019. The IJC   continues to work to maintain its policies in line with the Charter and  Code principles.    
 This recognition reflects our commitment to continuously improving our human resources policies in line with the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers.
 The HRS4R has the main objective of ensuring that research centers of excellence implement and respect the requirements of the European Charter for Researchers and the Code of Conduct for hiring researchers (from here on referred to as the Charter and Code) within their human resources policies.
This EC  initiative aims to promote training, professional development, and mobility for all European scientists. The IJC supports these values and principles, which will not only serve to strengthen its internal policies but will actively stimulate excellent research and firmly situate the organization as an institution with a stimulating working environment that favors the development of its scientists.

IJC is an equal-opportunity employer.  We evaluate qualified applicants without  regard to race, color, religion, sex,   national origin, disability, and other legally protected characteristics
We are looking forward to hearing from you!
Thank you for your interest in IJC. Please fill out the following short form. 
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